Research Article Open Access

Immunologic Response to Hepatitis B Vaccine in Health Care Workers: A Screening Program and Evaluation of Some Host-Related Factors Role

Mojtaba Varshochi1 and Roghayyeh Mahmodian2
  • 1 Infectious Diseases and Tropical Medicine Research Center, Iran
  • 2 Tabriz University of Medical Sciences, Iran

Abstract

Problem statement: To evaluation the immunologic response to hepatitis B vaccine in health care’s workers and effects of host-related factors? Approach: In a cross sectional descriptive analytic study carried out on the medical staff of Tabriz Shahid Madani Hospital in 2009-2010, we evaluated the immunologic response of the staff to vaccination against Hepatitis B and factors affecting it. Results: The mean antibody titer in the studied medical staff was 366.76±169.714 IU L-1. 2.05% were in “no response” group, 1.46% in “Low response” group and 96.49% in “Good response” group. Conclusion: Immunological response in the smoking staff was significantly less (p < 0.001) but no significant difference was observed in the response between genders (p = 0.127) and no case of hyperlipidemia was reported. There was a significant reverse linear relation between age and antibody titer in the studied staff (p = 0.003, R = 0.162) but no significant linear relation was observed between weight, height and BMI and antibody titer.

American Journal of Immunology
Volume 7 No. 1, 2011, 12-16

DOI: https://doi.org/10.3844/ajisp.2011.12.16

Submitted On: 18 August 2011 Published On: 17 September 2011

How to Cite: Varshochi, M. & Mahmodian, R. (2011). Immunologic Response to Hepatitis B Vaccine in Health Care Workers: A Screening Program and Evaluation of Some Host-Related Factors Role. American Journal of Immunology, 7(1), 12-16. https://doi.org/10.3844/ajisp.2011.12.16

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Keywords

  • Hepatitis B vaccines
  • occupational diseases
  • prevention and control
  • linear relation
  • antibody titer
  • factors affecting
  • immunologic response
  • analytic study
  • host-related factors