AJI Cover
Frequency: Continuous
ISSN: 1553-619X (Print)
ISSN: 1558-3775 (Online)
Research Article Open Access

An Analysis of the Creatine Kinase Isoenzyme and Cardiac Troponin T Levels in a Polymyositis Patient

R.M. Golding1, L.G.F. Giles2 and E.M. Sokoya3
  • 1 The University of New South Wales, Australia
  • 2 Murdoch University, Australia
  • 3 Australia and James Cook University of North Queensland, Australia

Abstract

From an extensive model developed to interpret physiological processes we are able to show that the observed elevated creatine kinase-myoglobin (CK-MB) and serum concentration of cardiac troponin T (cTnT) values for a particular patient are associated with the inflammatory disease, polymyositis, and not myocardial injury. This highlights that caution must be exercised in using elevated CK-MB and cTnT levels as evidence for myocardial damage in patients with chronic muscle degeneration such as polymyositis.

American Journal of Immunology
Volume 4 No. 1, 2008, 1-7

DOI: https://doi.org/10.3844/ajisp.2008.1.7

Submitted On: 23 March 2008 Published On: 31 March 2008

How to Cite: Golding, R., Giles, L. & Sokoya, E. (2008). An Analysis of the Creatine Kinase Isoenzyme and Cardiac Troponin T Levels in a Polymyositis Patient. American Journal of Immunology, 4(1), 1-7. https://doi.org/10.3844/ajisp.2008.1.7

Open AccessCopyright: © 2008 R.M. Golding, L.G.F. Giles and E.M. Sokoya. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

  • 4,557 Views
  • 4,083 Downloads
  • 0 Citations

Download

Keywords

  • Polymyositis
  • prednisolone
  • blood pressure
  • heart rate
  • erythrocyte sedimentation rate
  • creatine kinase
  • creatine kinase isoenzyme
  • cardiac troponin T