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Frequency: Quarterly
ISSN: 1553-6203 (Print)
ISSN: 1558-6340 (Online)
Research Article Open Access

POST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINE

Vidyanand Rabi Das1, Dharmendra Singh1, Krishna Murti2, Sushmita Das1, Pradeep Das1 and Krishna Pandey3
  • 1 Rajendra Memorial Research Institute of Medical Sciences, India
  • 2 National Institute of Pharmacy and Education Research, India
  • 3 Rajendra Memorial Research Institute of Medical Sciences , India

Abstract

Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and PKDL by 2018. PKDL diagnosis and management has not been addressed properly. In this case report we have described a case of PKDL with ulcer and atypical presentation who was subsequently diagnosed by demonstration of Leishmania donovani bodies in the skin snips through microscopy, kinetoplast-DNA nested PCR and clinically. The patient was treated with miltefosine capsules in the dose of 50 mg twice-a-day for twelve-weeks and responded completely. This case report assumes great importance as prompt diagnosis and treatment of PKDL is essential in the kala-azar elimination program.

American Journal of Infectious Diseases
Volume 10 No. 2, 2014, 50-55

DOI: https://doi.org/10.3844/ajidsp.2014.50.55

Submitted On: 28 February 2014 Published On: 2 April 2014

How to Cite: Das, V. R., Singh, D., Murti, K., Das, S., Das, P. & Pandey, K. (2014). POST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINE. American Journal of Infectious Diseases, 10(2), 50-55. https://doi.org/10.3844/ajidsp.2014.50.55

Open AccessCopyright: © 2014 Vidyanand Rabi Das, Dharmendra Singh, Krishna Murti, Sushmita Das, Pradeep Das and Krishna Pandey. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • PKDL
  • VL
  • Miltefosine
  • Ulcer
  • Kala-Azar Elimination Program