Research Article Open Access

Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals

Livia Maria Gonçalves Rossi1 and Paula Rahal1
  • 1 São Paulo State University, Brazil

Abstract

Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.

American Journal of Infectious Diseases
Volume 10 No. 4, 2014, 179-183

DOI: https://doi.org/10.3844/ajidsp.2014.179.183

Submitted On: 22 December 2014 Published On: 7 January 2015

How to Cite: Gonçalves Rossi, L. M. & Rahal, P. (2014). Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals. American Journal of Infectious Diseases, 10(4), 179-183. https://doi.org/10.3844/ajidsp.2014.179.183

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Keywords

  • Hepatitis C Virus
  • Resistant Mutants
  • Therapy
  • Direct Acting-Antiviral