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Frequency: Quarterly
ISSN: 1553-6203 (Print)
ISSN: 1558-6340 (Online)
Research Article Open Access

Circulation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in Mexico

Carlos A. Vazquez-Chacon1, Armando Martinez-Guarneros1, Susana Balandrano Campos1, Julieta Luna Herrera2, Claudia Bäcker1, Livia Maria Gonçalves Rossi3, Karina Ruiz-Tovar1, Salvador Fonseca-Coronado4, Juan C. Carpio-Pedroza1, Gilberto Vaughan1 and Alejandro Escobar-Gutierrez1
  • 1 Instituto de Diagnóstico y Referencia Epidemiológicos, Mexico
  • 2 Instituto Politécnico Nacional, Mexico
  • 3 São Paulo State University, Brazil
  • 4 Universidad Nacional Autónoma de México, Mexico

Abstract

Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB isolates, (58%) were classified as MDR exclusively, (33%) were Pre-XDR and (9%) were assigned as XDR. The results confirmed the circulation of Pre-XDR and XDR-TB in Mexico. Surveillance and drug-susceptibility testing should be improved in Mexico to monitor the circulation of XDR strains.

American Journal of Infectious Diseases
Volume 10 No. 4, 2014, 174-178

DOI: https://doi.org/10.3844/ajidsp.2014.174.178

Submitted On: 24 October 2014 Published On: 7 January 2015

How to Cite: Vazquez-Chacon, C. A., Martinez-Guarneros, A., Campos, S. B., Herrera, J. L., Bäcker, C., Gonçalves Rossi, L. M., Ruiz-Tovar, K., Fonseca-Coronado, S., Carpio-Pedroza, J. C., Vaughan, G. & Escobar-Gutierrez, A. (2014). Circulation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in Mexico. American Journal of Infectious Diseases, 10(4), 174-178. https://doi.org/10.3844/ajidsp.2014.174.178

Open AccessCopyright: © 2014 Carlos A. Vazquez-Chacon, Armando Martinez-Guarneros, Susana Balandrano Campos, Julieta Luna Herrera, Claudia Bäcker, Livia Maria Gonçalves Rossi, Karina Ruiz-Tovar, Salvador Fonseca-Coronado, Juan C. Carpio-Pedroza, Gilberto Vaughan and Alejandro Escobar-Gutierrez. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Tuberculosis
  • MDR
  • Pre-XDR
  • XDR
  • Mexico